Peptides
PT-141 (Bremelanotide)
In plain language
An injectable medication (brand name Vyleesi) approved specifically to treat low sexual desire in premenopausal women.
Hard safety warning
Not a real, regulated product — do not buy this online.
Is it an approved medication?
Yes — approved medication
YES, but only for that one specific use - approved by the FDA as Vyleesi
How strong is the evidence?
Strong for its approved use; essentially untested for the ways it is often marketed online (general/male use)
The main thing to know
Common side effects include nausea and flushing. Off-label online versions are not the same regulated product.
Mechanism
Melanocortin 4 receptor (MC4R) agonist; acts centrally on sexual desire pathways rather than vascular mechanisms.
Potential benefits
- FDA-approved for hypoactive sexual desire disorder in premenopausal women
- Off-label male/recreational use poorly evidenced
Regulatory status
FDA-approved (Vyleesi) for the approved indication only; off-label use not regulated